Chargers vs Ravens NFL Picks and Predictions

Our Chargers vs Ravens NFL picks and predictions cover the (0-8) Los Angeles Chargers at the (4-5) Baltimore Ravens on Monday, November 16th at 8:15 PM ET. Check out our full Week 10 NFL Schedule for odds and predictions on every game this week.
All of the odds, matchup grades, injury data, and betting trends referenced below come from HOF's sports betting research app, which tracks live lines and team/player data to help bettors make more informed decisions. For our top touchdown scorer prop picks and DFS plays in this game, check out our Chargers vs Ravens NFL Player Props and DFS Picks article.
Table of Contents
Odds
Baltimore is favored at -5 (-107) on the spread with a -208 moneyline, while Los Angeles sits at +5 (-106) on the spread and +201 on the moneyline. The total is set at 38.5, with the over priced at -110 and the under at +100.
Matchup Breakdown
Los Angeles' offense ranks near the bottom of the league against Baltimore's defense, ranking 18th in Rush Yards at 111.1, 26th in Pass Yards, 27th in Rush TDs, 28th in Rush+Rec Yards, 31st in Pass TDs, and 32nd in Anytime TDs. Baltimore's defense ranks 11th against Pass TDs, 13th against Rush Yards, 16th against Rush+Rec Yards, 21st against Anytime TDs, 22nd against Pass Yards, and 29th against Rush TDs, and J. Herbert carries a B- matchup grade with a projection of 198.9 passing yards, 0.8 touchdowns, and 1.4 interceptions, though he is listed as questionable with a finger injury.
Baltimore's offense is built on the ground against Los Angeles' defense, ranking 4th in Rush Yards at 137.8 and 8th in Rush TDs, but 20th in both Rush+Rec Yards and Anytime TDs, 23rd in Pass Yards, and 25th in Pass TDs. Los Angeles' defense ranks 7th against both Pass Yards and Pass TDs, 14th against Rush+Rec Yards, 16th against Anytime TDs, 23rd against Rush Yards, and 30th against Rush TDs, and J. Brissett carries a D- matchup grade with a projection of 214.9 passing yards, 1.3 touchdowns, and 0.9 interceptions, with L. Jackson listed as out (surgery).
Injury Report
J. Herbert (LAC) – Finger, Questionable (11/8).
L. McConkey (LAC) – Back, Questionable (11/8).
D. Njoku (LAC) – Lower Leg, Out (11/8).
L. Jackson (BAL) – Surgery, Out (11/8).
T. Huntley (BAL) – Sprain, Out (11/5).
A. Isaac (BAL) – Hamstring, Questionable (11/5).
Betting Trends
Los Angeles has covered the +4.5 spread in 0% of its games and hit the moneyline in 0%, while Baltimore has covered the -4.5 spread in 33% of its games and hit the moneyline in 44%. Baltimore holds the better record at 4-5 versus Los Angeles's 0-8.
Our Pick
Pick: Under 38.5 (-100). Both offenses rank poorly in the categories that drive scoring: Los Angeles ranks 32nd in Anytime TDs and 31st in Pass TDs, while Baltimore ranks 20th in Anytime TDs and 25th in Pass TDs, and the two quarterback projections come in at 198.9 and 214.9 passing yards. Baltimore's rushing attack ranks 4th in Rush Yards against a Chargers defense that ranks 30th against Rush TDs, so a few scores are likely, but a 38.5-point total is still a high bar for these two offenses.
How We Made Our Chargers vs Ravens NFL Picks and Predictions
Our Chargers vs Ravens NFL picks and predictions are built directly from HOF's sports betting research app rather than gut feel or outside commentary. For every Week 10 matchup, we start with HOF's live point spread, moneyline, and total, then layer in the team grades HOF assigns across offense and defense to see where a real statistical edge exists. From there, we cross-reference HOF's injury report to confirm which players are active, questionable, or out, since a single absence can shift a matchup grade significantly.
We also check HOF's betting trends data — how each team has performed against the spread and the total recently — to see whether the market is lining up with or against the statistical picture. Only after weighing the odds, the matchup grades, the injury report, and the betting trends together do we land on the spread, moneyline, or total pick we publish here. We don't publish a pick without a clear data-backed reason behind it, and we update our numbers as HOF's app updates its own lines and grades throughout the week.
Because lines and injury designations can move between now and kickoff, we recommend checking HOF's app for the latest numbers before placing any wager. A pick that looks strong at one number can lose its edge at another, so the price you can get matters just as much as the side you like.