Vikings vs Buccaneers NFL Picks and Predictions

The Minnesota Vikings (2-0) hit the road to take on the Tampa Bay Buccaneers (1-1) in a Week 3 matchup on Sunday, September 27th at 4:05 PM ET. Check out our full Week 3 NFL Schedule for odds and predictions on every game this week.

All of the odds, matchup grades, injury data, and betting trends referenced below come from HOF's sports betting research app, which tracks live lines and team/player data to help bettors make more informed decisions.

Odds

Spread: Vikings -1.5 (+102) | Buccaneers +1.5 (-105)

Moneyline: Vikings -111 | Buccaneers +108

Total: 42.5 | Over -104 | Under -100

Matchup Breakdown

The Vikings offense grades out near the bottom of the league across the board this week, ranking 22nd, 24th, 24th, 24th, 21st, and 24th in HOF's tracked team categories. The Buccaneers defense grades out considerably stronger on the other side of the ball, checking in at 14th, 8th, 16th, 12th, 6th, and 16th in those same metrics. That gap favors Tampa Bay's defense in this spot.

At quarterback, Baker Mayfield carries an A matchup grade against Minnesota this week, with HOF projecting 199 passing yards, 1.3 passing touchdowns, and 0.9 interceptions. Carson Wentz grades out considerably lower at a C+ against the Buccaneers, projected for 133 passing yards, 3 passing touchdowns, and 0 interceptions.

For more data on players specifically, check out our Vikings vs Buccaneers player props.

Injury Report

J. Mason (MIN) – Surgery, Out (9/16)

D. Sills (TB) – Undisclosed, Out (8/31)

K. Murray (MIN) – Concussion, Questionable (9/17)

B. Yurosek (MIN) – Undisclosed, Out (9/8)

J. Jones (MIN) – Suspension, Out (8/25)

D. Fleming (MIN) – Undisclosed, Questionable (9/3)

Betting Trends

Moneyline: 56% of bettors are backing the Vikings moneyline (+105), while 44% are on the Buccaneers (-116).

Spread: 56% are on Vikings +1.5, compared to 39% on Buccaneers -1.5.

Total: 39% of Vikings games and 44% of Buccaneers games are trending Over this season, while 61% of Vikings games and 56% of Buccaneers games are trending Under.

Our Pick

Tampa Bay holds a clear defensive edge over Minnesota's struggling offense, and Baker Mayfield's matchup grade dwarfs what Carson Wentz is projected for this week. We're siding with the home team to handle business here.

Pick: Buccaneers -1.5