Seahawks vs Cardinals NFL Player Props and DFS Picks
Looking for the best Seahawks vs Cardinals player props for Sunday's Week 2 NFC West matchup? We break down usage rates, target share, and matchup grades for the key skill players on both sides to help you build your DFS lineup and prop card. Check out our full Week 2 NFL Schedule for odds and predictions on every game this week.
You can dig deeper into usage share, target rates, and matchup grades yourself with our sports betting research app, which we used to pull every number in this breakdown.
Table of Contents
Seahawks vs Cardinals QB Props
This is the storyline to watch before setting any prop card for this game: Seattle's Sam Darnold (hip) is doubtful, and backup Jalen Milroe is already out via coach's decision, leaving real uncertainty about who takes snaps for the Seahawks. His projection, listed at 194.8 passing yards, 1.1 touchdowns, and 0.4 interceptions with a B Matchup grade, should be treated with caution until his status is confirmed.
Arizona's Jacoby Brissett carries a C Matchup grade, projected for 276.7 passing yards, 1.9 touchdowns, and 0.7 interceptions, giving him solid volume even in a game his team is expected to trail in.
Seahawks vs Cardinals Receiver and Rusher Props
Arizona's Marvin Wilson leads all skill players in this matchup with a projection of 87 total yards and 0.6 touchdowns despite a D- Matchup grade, while tight end Trey McBride carries the top matchup grade of the game at A-, projected for 81.8 total yards and 0.7 touchdowns.
Seattle's Jaxon Smith-Njigba carries a C+ Matchup grade with a projection of 80 total yards and 0.6 touchdowns, while in the backfield, Zach Charbonnet's absence pushes Jarquez Price into the lead role, projected for 58 total yards on an A- Matchup grade, though without a touchdown projection.
Seahawks vs Cardinals Usage Share Breakdown
Seattle's passing game is dominated by one player: Jaxon Smith-Njigba leads the team at 35.4% target share (9.5 targets per game), well ahead of Cooper Kupp at 17.7% (4.8 targets) and Alex Barner at 13.6% (3.7 targets). Tory Horton (11.9% target share) is already ruled out, which should push a few extra targets toward Rashid Shaheed, who sits at 10.9% (3.0 targets).
Arizona's target distribution is led by Trey McBride at 27.4% (9.9 targets), followed by Marvin Wilson at 20.4% (7.4 targets) and Michael Harrison at 18.0% (6.1 targets). Trey Benson (12.5% target share) is already ruled out, and with James Conner also out, Arizona's backfield touches become harder to project heading into Sunday.
Seahawks vs Cardinals Injury Impact on Props
This game has more injury-driven uncertainty than most on the Week 2 slate. Seattle's quarterback situation is unresolved with Darnold doubtful and Milroe out, while both Charbonnet and Horton are already ruled out. Arizona's backfield is even more depleted, with both Conner and Benson out and Reiman also sidelined at tight end. Bettors and DFS players should check final injury designations close to kickoff before locking in props for this one.
Best Seahawks vs Cardinals Player Prop Picks
Our top plays for this matchup lean toward the players with clear roles regardless of the quarterback situation: Jaxon Smith-Njigba's target share makes him a strong anchor in any DFS build, while Trey McBride's elite matchup grade gives him strong appeal on the Arizona side. For the full game outlook, be sure to check our Seahawks vs Cardinals picks for our against-the-spread and total recommendations.