Cowboys vs Packers NFL Picks and Predictions
Our Cowboys vs Packers NFL picks and predictions cover the (2-3) Dallas Cowboys at the (3-2) Green Bay Packers on Sunday, October 18th at 8:20 PM ET. Check out our full Week 6 NFL Schedule for odds and predictions on every game this week.
All of the odds, matchup grades, injury data, and betting trends referenced below come from HOF's sports betting research app, which tracks live lines and team/player data to help bettors make more informed decisions. For our top touchdown scorer prop picks and DFS plays in this game, check out our Cowboys vs Packers NFL Player Props and DFS Picks article.
Table of Contents
Odds
Green Bay is favored at -1.5 (+105) on the spread with a -108 moneyline, while Dallas sits at +1.5 (-106) on the spread and +104 on the moneyline. The total is set at 53.5, with the over priced at +106 and the under at -108 — a near pick'em on Sunday night with one of the highest totals of the week.
Matchup Breakdown
Dallas's offense grades out well against Green Bay's defense, ranking 5th in Pass Yards, 7th in Anytime TDs, 7th in Rush TDs, and 11th in Rush+Rec Yards, though it ranks 30th in Rush Yards. Green Bay's defense ranks 5th against Pass Yards and 8th against Rush+Rec Yards, but it ranks 30th against Rush TDs, and Prescott carries a D- matchup grade with a projection of 276.2 passing yards and 1.8 touchdowns.
Green Bay's offense grades out well through the air against Dallas's defense, ranking 4th in Pass Yards and 9th in Pass TDs, though it ranks 32nd in Rush Yards. Dallas's defense is the weakest unit in this matchup, ranking 31st against Rush+Rec Yards, 32nd against Rush Yards, 26th against Anytime TDs, and 25th against Pass TDs, and Love carries a C matchup grade with a projection of 281.6 passing yards and 2 touchdowns.
Injury Report
C. Lamb (DAL) – Quadriceps, Questionable (10/9).
C. Brooks (GB) – Ankle, Out (10/10).
S. Moore (GB) – Ankle, Questionable (10/11).
J. Reed (GB) – Surgery, Out (9/30).
Betting Trends
Dallas has covered the +1.5 spread in 40% of its games and hit the moneyline in 40%, while Green Bay has covered the -1.5 spread in 60% of its games and hit the moneyline in 60%. Green Bay holds the better record at 3-2.
Our Pick
Pick: Over 52.5. Dallas's defense ranks 31st against Rush+Rec Yards and 32nd against Rush Yards, and Green Bay's offense ranks 4th in Pass Yards, while Dallas's offense ranks 7th in Anytime TDs and 5th in Pass Yards against a Green Bay defense that ranks 30th against Rush TDs. Both quarterbacks project for more than 275 passing yards. We like this game to clear a high total.
How We Made Our Cowboys vs Packers NFL Picks and Predictions
Our Cowboys vs Packers NFL picks and predictions are built directly from HOF's sports betting research app rather than gut feel or outside commentary. For every Week 6 matchup, we start with HOF's live point spread, moneyline, and total, then layer in the team grades HOF assigns across offense and defense to see where a real statistical edge exists. From there, we cross-reference HOF's injury report to confirm which players are active, questionable, or out, since a single absence can shift a matchup grade significantly.
We also check HOF's betting trends data — how each team has performed against the spread and the total recently — to see whether the market is lining up with or against the statistical picture. Only after weighing the odds, the matchup grades, the injury report, and the betting trends together do we land on the spread, moneyline, or total pick we publish here. We don't publish a pick without a clear data-backed reason behind it, and we update our numbers as HOF's app updates its own lines and grades throughout the week.
Because lines and injury designations can move between now and kickoff, we recommend checking HOF's app for the latest numbers before placing any wager. A pick that looks strong at one number can lose its edge at another, so the price you can get matters just as much as the side you like.