Colts vs Chiefs NFL Player Props and DFS Picks
Looking for the best Colts vs Chiefs player props for Sunday night's Week 2 matchup? We break down usage rates, target share, and matchup grades for the key skill players on both sides to help you build your DFS lineup and prop card. Check out our full Week 2 NFL Schedule for odds and predictions on every game this week.
You can dig deeper into usage share, target rates, and matchup grades yourself with our sports betting research app, which we used to pull every number in this breakdown.
Table of Contents
Colts vs Chiefs QB Props
The biggest question mark on this week's prop card belongs to Patrick Mahomes, who is questionable after a procedure. If he plays, he carries an A Matchup grade with projections of 255.3 passing yards, 1.1 touchdowns, and 1.3 interceptions, but his props should be treated with caution until his status is confirmed closer to kickoff.
Indianapolis' Daniel Jones carries a D Matchup grade, projected for 218.5 passing yards, 1.5 touchdowns, and 0.8 interceptions against a Kansas City defense that grades out well against the pass.
Colts vs Chiefs RB and WR Props
Indianapolis' Jonathan Taylor leads all skill players in this matchup with a projection of 108.1 total yards and 0.9 touchdowns, though he carries a D Matchup grade against a stout Chiefs run defense. Kansas City's K. Walker carries a D+ Matchup grade, projected for 99.3 total yards and 0.5 touchdowns.
Kansas City's Rashee Rice carries an A Matchup grade, the best of any skill player in this game, projected for 78.4 total yards and 0.6 touchdowns, making him a strong anchor regardless of who's throwing him the ball.
Colts vs Chiefs Usage Share Breakdown
Indianapolis' target distribution is led by T. Warren at 21.2% (6.6 targets), followed closely by Alec Pierce at 18.0% (5.6 targets), though Pierce is questionable with a heel injury. Josh Downs sits at 17.7% (5.5 targets), with Jonathan Taylor adding 10.4% (3.2 targets) out of the backfield.
Kansas City's passing game is heavily concentrated on Rashee Rice, who leads at 28.8% (9.8 targets), well ahead of Travis Kelce at 19.7% (6.4 targets) and Xavier Worthy at 16.1% (5.2 targets).
Colts vs Chiefs Injury Impact on Props
Beyond the Mahomes situation, Kansas City is missing Jaylen Caldwell, Jason Holiday, and Jack Gyllenborg, none of whom factor heavily into the target share breakdown. Indianapolis has two questionable pass catchers in Alec Pierce (heel) and Drew Ogletree (neck); if either is limited, expect more volume for Josh Downs and M. Alie-Cox in the Colts passing game.
Best Colts vs Chiefs Player Prop Picks
Our top plays for this matchup lean toward the players with the clearest roles regardless of the Mahomes situation: Rashee Rice's target share makes him a strong anchor in any DFS build, while Jonathan Taylor's workload gives him a solid floor on the ground. Monitor the Mahomes injury report closely before finalizing any Chiefs passing props. For the full game outlook, be sure to check our Colts vs Chiefs picks for our against-the-spread and total recommendations.