Giants vs Rams NFL Picks and Predictions
The New York Giants travel to Los Angeles as big underdogs against the Rams in the Week 2 Monday Night Football finale. We break down the odds, matchup numbers, injuries, and betting trends to land on the best Giants vs Rams pick. For the rest of the slate, check out our full Week 2 NFL Schedule with odds and predictions for every game.
You can explore all of this matchup data yourself with our sports betting research app, which we used to pull every stat in this breakdown.
Table of Contents
Giants vs Rams Odds and Betting Lines
Los Angeles is a heavy home favorite, with the Rams listed at -9.5 (-106) and New York getting 9.5 points at +9.5 (-104). The moneyline has the Giants at +441 and the Rams at -484, while the total sits at 48.5, with the over priced at -106 and the under at -110.
A near double-digit spread for the Monday night finale reflects the gap in overall talent between these two rosters, though the underlying matchup numbers are closer than the moneyline suggests.
Giants vs Rams Matchup Breakdown
New York's offense holds up reasonably well against the Rams defense in a few key areas. The Giants rank 23rd in total rush and receiving yards (309.5) against a Los Angeles defense that ranks 20th in yards allowed (336.5). New York ranks 21st in passing yards (204.4) facing a Rams defense that ranks 22nd against the pass (225.6 allowed), and a strong 5th in rushing yards (130.2) against a Los Angeles run defense that ranks 11th (110.2 allowed).
Touchdown production is a mixed bag: the Giants rank 14th in anytime touchdowns (2.5) against a Rams defense that ranks 10th in touchdowns allowed (2.2), and an excellent 4th in rushing touchdowns (1.3), though Los Angeles' defense ranks 3rd in rushing touchdowns allowed (0.6). New York's passing touchdown output ranks 25th (1.2) against a Rams defense ranked 21st in passing touchdowns allowed (1.6).
At quarterback, Los Angeles' Matthew Stafford carries a C+ Matchup grade with projections of 308.6 passing yards, 2.5 touchdowns, and 0.7 interceptions. New York's Jaxson Dart carries a B Matchup grade, projected for 185.1 passing yards, 1 touchdown, and 0.3 interceptions.
Giants vs Rams Injury Report
New York's top receiver Malik Nabers (surgery) is questionable after appearing on the report on 9/9, a significant storyline given his role in the passing game. The Giants are also missing Cordale Austin (knee), Gunner Olszewski (surgery), and Ray Robertson-Harris (surgery), all ruled out. Los Angeles has two injuries of its own, with James Watson (toe) questionable and Marcus Caldwell (undisclosed) already out.
Giants vs Rams Betting Trends
New York has covered the spread in 65% of its games, while Los Angeles has covered as a favorite in just 40% of its games. Straight up, the Giants have won only 24% of their games and the Rams have won 70% of theirs.
The total has trended over in Los Angeles games (60% over) but closer to even in New York games (47% over), which points toward the over as the side with more recent momentum on the Rams' side.
Final Prediction and Pick
With New York's strong rushing numbers and solid cover rate as an underdog, the Giants getting 9.5 points holds appeal for spread bettors even in a game Los Angeles is expected to control. The Malik Nabers injury designation is worth monitoring closely, as his absence would be a meaningful blow to New York's passing attack. On the total, Los Angeles' strong offensive form points toward the over as the more attractive side.
For a closer look at Monday night's skill-position volume, be sure to check our Giants vs Rams player props breakdown for the best individual player bets in this matchup.