Cowboys vs Eagles NFL Picks and Predictions
Our Cowboys vs Eagles NFL picks and predictions cover the (2-4) Dallas Cowboys at the (2-4) Philadelphia Eagles on Monday, October 26th at 8:15 PM ET. Check out our full Week 7 NFL Schedule for odds and predictions on every game this week.
All of the odds, matchup grades, injury data, and betting trends referenced below come from HOF's sports betting research app, which tracks live lines and team/player data to help bettors make more informed decisions. For our top touchdown scorer prop picks and DFS plays in this game, check out our Cowboys vs Eagles NFL Player Props and DFS Picks article.
Table of Contents
Odds
Dallas is favored at -4.5 (-108) on the spread with a -198 moneyline, while Philadelphia sits at +4.5 (-106) on the spread and +186 on the moneyline. The total is set at 44.5, with the over priced at -108 and the under at -108. Both teams enter the Monday night game at 2-4.
Matchup Breakdown
Dallas' offense grades out well against Philadelphia's defense, ranking 6th in Pass Yards, 7th in Rush TDs, 8th in Anytime TDs, and 13th in Rush+Rec Yards, though it ranks 31st in Rush Yards. Philadelphia's defense is vulnerable, ranking 28th against Rush TDs, 27th against Rush+Rec Yards, and 26th against Pass Yards, and Prescott carries a B+ matchup grade with a projection of 273.2 passing yards and 1.7 touchdowns.
Philadelphia's offense grades out near the bottom of the league against Dallas' defense, ranking 30th in Rush+Rec Yards, 29th in Rush Yards, 26th in Pass Yards, 23rd in Anytime TDs, and 21st in Rush TDs. Dallas' defense is also a weakness, ranking 32nd against Rush Yards, 30th against Rush+Rec Yards, and 23rd against both Anytime TDs and Pass Yards, and T. McKee carries a B- matchup grade with a projection of 215 passing yards and 1 touchdown.
Injury Report
J. Hurts (PHI) – Calf, Out (10/17).
S. Barkley (PHI) – Hamstring, Out (10/16).
T. Bigsby (PHI) – Surgery, Out (10/6).
W. Shipley (PHI) – Plantar Fasciitis, Out (10/16).
K. Turpin (DAL) – Ribs, Questionable (10/18).
Betting Trends
Dallas has covered the -4.5 spread in just 17% of its games and hit the moneyline in 33%, while Philadelphia has covered the +4.5 spread in 67% of its games and hit the moneyline in 33%. The trend data leans toward Philadelphia, but the injury report works against the Eagles.
Our Pick
Pick: Cowboys -4.5. This is a pick where the trend data and the matchup grades disagree: Dallas has covered in only 17% of its games and Philadelphia in 67%. We side with the matchups and the injury report. Dallas ranks 6th in Pass Yards against a Philadelphia defense ranked 26th against the pass, and Prescott carries a B+ matchup grade with a projection of 273.2 passing yards. Philadelphia's offense ranks 30th in Rush+Rec Yards, J. Hurts, S. Barkley, T. Bigsby, and W. Shipley are all out, and T. McKee projects for just 215 passing yards and 1 touchdown. We like the Cowboys to cover, with the caveat that the trend favors the Eagles.
How We Made Our Cowboys vs Eagles NFL Picks and Predictions
Our Cowboys vs Eagles NFL picks and predictions are built directly from HOF's sports betting research app rather than gut feel or outside commentary. For every Week 7 matchup, we start with HOF's live point spread, moneyline, and total, then layer in the team grades HOF assigns across offense and defense to see where a real statistical edge exists. From there, we cross-reference HOF's injury report to confirm which players are active, questionable, or out, since a single absence can shift a matchup grade significantly.
We also check HOF's betting trends data — how each team has performed against the spread and the total recently — to see whether the market is lining up with or against the statistical picture. Only after weighing the odds, the matchup grades, the injury report, and the betting trends together do we land on the spread, moneyline, or total pick we publish here. We don't publish a pick without a clear data-backed reason behind it, and we update our numbers as HOF's app updates its own lines and grades throughout the week.
Because lines and injury designations can move between now and kickoff, we recommend checking HOF's app for the latest numbers before placing any wager. A pick that looks strong at one number can lose its edge at another, so the price you can get matters just as much as the side you like.