NFL Week 16 Schedule, Odds, and Predictions (2026)

The 2026 NFL Week 16 schedule opens with the Houston Texans visiting the Philadelphia Eagles on Thursday, Dec. 24, before a Christmas Day tripleheader featuring Packers-Bears, Bills-Broncos, and Rams-Seahawks. The week continues with a full Sunday slate and concludes with the New York Giants visiting the Detroit Lions on Monday night.

Sunday's schedule includes Browns-Ravens, Chargers-Dolphins, Patriots-Jets, 49ers-Chiefs, Jaguars-Cowboys, and several other conference and divisional matchups. The early NFL Week 16 odds show Baltimore as the largest favorite on the supplied board, while several games have spreads of 1.5 points or less.

Below is the complete NFL schedule for Week 16, followed by an early look at NFL Week 16 odds and predictions. Betting lines are time-sensitive snapshots and can move considerably before kickoff.

NFL Week 16 Schedule

Here is the Week 16 NFL schedule for the 2026 season. All kickoff times below are Eastern Time.

• Houston Texans at Philadelphia Eagles — Thursday, Dec. 24, 8:15 p.m.
• Green Bay Packers at Chicago Bears — Friday, Dec. 25, 1:00 p.m.
• Buffalo Bills at Denver Broncos — Friday, Dec. 25, 4:30 p.m.
• Los Angeles Rams at Seattle Seahawks — Friday, Dec. 25, 8:15 p.m.
• Tampa Bay Buccaneers at Atlanta Falcons — Sunday, Dec. 27, 1:00 p.m.
• Cincinnati Bengals at Indianapolis Colts — Sunday, Dec. 27, 1:00 p.m.
• Washington Commanders at Minnesota Vikings — Sunday, Dec. 27, 1:00 p.m.
• Carolina Panthers at Pittsburgh Steelers — Sunday, Dec. 27, 1:00 p.m.
• Cleveland Browns at Baltimore Ravens — Sunday, Dec. 27, 1:00 p.m.
• Los Angeles Chargers at Miami Dolphins — Sunday, Dec. 27, 1:00 p.m.
• Arizona Cardinals at New Orleans Saints — Sunday, Dec. 27, 1:00 p.m.
• New England Patriots at New York Jets — Sunday, Dec. 27, 1:00 p.m.
• Tennessee Titans at Las Vegas Raiders — Sunday, Dec. 27, 4:05 p.m.
• San Francisco 49ers at Kansas City Chiefs — Sunday, Dec. 27, 4:25 p.m.
• Jacksonville Jaguars at Dallas Cowboys — Sunday, Dec. 27, 8:20 p.m.
• New York Giants at Detroit Lions — Monday, Dec. 28, 8:15 p.m.

The Week 16 NFL schedule features a full 16-game slate spread across four days. Texans-Eagles starts the week on Christmas Eve, followed by three Christmas Day games. Sunday carries 11 games, including Jaguars-Cowboys in prime time, before Giants-Lions closes the week Monday night.

NFL Week 16 Odds

The early NFL Week 16 odds provide betting markets for every matchup on the supplied board. The lines below are based on the odds supplied on Aug. 20, 2026 and should be treated as early snapshots rather than projected closing numbers.

Baltimore carries the largest spread of the week. The Ravens are approximately 10.5-point favorites against Cleveland and around -525 on the moneyline, while the Browns are approximately +375.

The Chargers are the next-largest favorite, laying roughly seven points on the road against Miami and priced around -355. Detroit is favored by approximately 6.5 points against the Giants, New England is around -6 against the Jets, and New Orleans is approximately -5.5 against Arizona.

Several games sit much closer to pick'em territory. Buffalo is approximately a one-point favorite at Denver, while Cincinnati is around -1 against Indianapolis. Tampa Bay is roughly a one-point favorite at Atlanta. Minnesota and Las Vegas are favored by approximately 1.5 points in their respective matchups.

The Christmas night Rams-Seahawks game is also priced extremely tightly. The supplied board shows Los Angeles around -110 on the moneyline and Seattle near -102, with the listed spreads sitting around one point.

The highest total belongs to Jaguars-Cowboys at approximately 52.5 points. Bengals-Colts follows at roughly 51.5, while Giants-Lions sits around 49.5. Texans-Eagles has the lowest listed total, with available numbers around 37.5 to 38.5.

NFL odds for Week 16 can change significantly because of injuries, team performance, playoff positioning, roster developments, and betting activity. Check current numbers in the Hall of Fame Bets sports betting app before making a wager.

NFL Week 16 Predictions

Early NFL Week 16 predictions are analytical leans rather than guarantees. These selections generally incorporate the supplied betting market but should be reassessed as injuries, late-season form, and playoff scenarios become clearer.

Texans at Eagles: Philadelphia gets the prediction. The Eagles are favored by approximately 2.5 points at home, while the early total is below 40 points.

Packers at Bears: Chicago gets a narrow Christmas Day lean. The Bears are approximately one-point home favorites, making this one of the closest games on the Week 16 board.

Bills at Broncos: Buffalo gets a slight prediction. The Bills are approximately one-point road favorites, and the market indicates little separation between these teams.

Rams at Seahawks: Los Angeles gets the narrowest of leans. The early market is essentially around pick'em territory, so this matchup should be revisited as Week 16 approaches.

Buccaneers at Falcons: Tampa Bay gets the pick. The Buccaneers are approximately one-point road favorites, another indication of how competitive the early market expects this matchup to be.

Bengals at Colts: Cincinnati gets the prediction. The Bengals are favored by roughly one point on the road, while the 51.5-point total is one of the highest of Week 16.

Commanders at Vikings: Minnesota gets a narrow lean. The Vikings are approximately 1.5-point home favorites, with Washington priced close behind on the moneyline.

Panthers at Steelers: Pittsburgh gets the prediction. The Steelers are favored by roughly 3.5 points at home, while the total is approximately 40.5.

Browns at Ravens: Baltimore gets the pick. The Ravens are favored by approximately 10.5 points, making them the biggest favorite on the supplied Week 16 board.

Chargers at Dolphins: Los Angeles gets the prediction. The Chargers are approximately seven-point road favorites and around -355 on the moneyline.

Cardinals at Saints: New Orleans gets the early pick. The Saints are favored by approximately 5.5 points at home, giving them one of the stronger advantages on the Week 16 board.

Patriots at Jets: New England gets the prediction. The Patriots are favored by roughly six points on the road and around -275 on the moneyline.

Titans at Raiders: Las Vegas gets a narrow lean. The Raiders are approximately 1.5-point home favorites, so the early market sees this as a competitive game.

49ers at Chiefs: Kansas City gets the prediction. The Chiefs are favored by approximately three points at home, with the total sitting around 47.5.

Jaguars at Cowboys: Dallas gets the Sunday night pick. The Cowboys are approximately three-point home favorites, while the 52.5-point total is the highest on the Week 16 board.

Giants at Lions: Detroit gets the Monday night prediction. The Lions are favored by approximately 6.5 points at home and around -275 on the moneyline.

For deeper matchup analysis throughout the season, see our NFL picks.

Who Is Favored to Win in NFL Week 16?

Based on the supplied early NFL Week 16 odds, the Baltimore Ravens are the biggest favorite, laying approximately 10.5 points against the Cleveland Browns. The Chargers are next at roughly -7 against Miami, followed by Detroit at approximately -6.5 against the Giants.

New England is favored by roughly six points against the Jets, while New Orleans is around -5.5 against Arizona.

Week 16 also features several games with very small spreads. Packers-Bears, Bills-Broncos, Buccaneers-Falcons, Bengals-Colts, Rams-Seahawks, Commanders-Vikings, and Titans-Raiders are all priced within roughly 1.5 points on the supplied board.

Being favored does not guarantee a victory. Early point spreads represent market expectations at a specific moment and can change considerably before late December.

What Are the Odds for NFL Week 16?

NFL Week 16 odds generally center on three primary markets: the moneyline, point spread, and game total. The spread represents the expected margin between the teams, the moneyline prices each team's chances of winning outright, and the total sets a number for their combined points.

The early Week 16 spreads range from around one point in several closely priced games to 10.5 points for Browns-Ravens. Chargers-Dolphins carries another substantial spread at approximately seven points, while Giants-Lions is around 6.5.

Game totals range from below 40 points for Texans-Eagles to approximately 52.5 for Jaguars-Cowboys. Bengals-Colts also carries a high total at roughly 51.5, while Giants-Lions is around 49.5.

These numbers are early market snapshots rather than fixed prices. Bettors should compare updated NFL odds Week 16 markets closer to kickoff, particularly with playoff positioning and late-season injuries potentially affecting the lines.

Who Is Predicted to Win Week 16 in the NFL?

Our early Week 16 NFL predictions lean toward Philadelphia, Chicago, Buffalo, the Rams, Tampa Bay, Cincinnati, Minnesota, Pittsburgh, Baltimore, the Chargers, New Orleans, New England, Las Vegas, Kansas City, Dallas, and Detroit.

Those selections generally follow the early favorites on the supplied board, but several games are effectively priced near toss-up territory. Week 16 is also late enough in the season that injuries, playoff qualification, seeding scenarios, and potential lineup decisions could materially change the outlook.

The Week 16 NFL schedule combines a full 16-game slate with Christmas football and several tightly priced matchups. Baltimore enters the early market as the week's largest favorite, Jaguars-Cowboys carries the highest total, and Giants-Lions closes the schedule on Monday night.